Directions to Paychex, Inc. Directions to Paychex, Inc. Search | Advanced Search | New Members | Coupons and Discounts | All Categories Business & Professional Services >> Payroll Services Paychex, Inc. 911 Panorama Trail SouthRochester, NY 14625 | map (331) 643-7227 Visit Site Get directions to: Paychex, Inc., 911 Panorama Trail South, Rochester NY Get directions from: Click to Print This Page Need to update your categories or expand your listing? Or want to learn how your business can become a part of the Chamber? Contact us at membership@columbus.org for assistance.